Level of evidence according to the AMSTAR 2 assessment tool
Level | Description |
---|---|
High | No or one non-critical weakness: the systematic review provides an accurate and comprehensive summary of the results of the available studies that address the question of interest. |
Moderate | More than one non-critical weakness |
Low | One critical flaw with or without non-critical weaknesses: the review has a critical flaw and may not provide an accurate and comprehensive summary of the available studies that address the question of interest. |
Critically low | More than one critical flaw with or without non-critical weaknesses: the review has more than one critical flaw and should not be relied on to provide an accurate and comprehensive summary of the available studies. |
AMSTAR 2, A Measurement Tool to Assess Systematic Reviews.
*Multiple non-critical weaknesses may diminish the confidence in the review, and it may be appropriate to move the overall appraisal down from moderate to low confidence.