Korean J Orthod
Published online February 3, 2021
Copyright © The Korean Association of Orthodontists.
Diego Junior da Silva Santosa,c,d; Jonas Capelli Jr.b,d
a. PhD Student, Department of Preventive and Community Dentistry, School of Dentistry, Rio de Janeiro State University, Rio de Janeiro, Brazil
b. Full Professor of Orthodontics, Department of Preventive and Community Dentistry, School of Dentistry, Rio de Janeiro State University, Rio de Janeiro, Brazil
c. Private practice
d. Brazilian Board of Orthodontics Certificated
Correspondence to:Diego Junior da Silva Santos
Address: Avenida Ataulfo de Paiva, 1460, apt 601, Leblon, Rio de Janeiro-RJ, Brazil
CEP: 22440-035
Phone: +55 (21) 98027-2082; e-mail: diegorsdrj@gmail.com.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Objectives: To compare the effectiveness of ibuprofen, acetaminophen, and chewing gum for orthodontic pain relief and to assess if chewing gum can be a nonpharmacologic alternative for orthodontics pain relief. Methods: 106 patients were enrolled. The eligibility criteria were age ≥12 years, body mass >50 kg, either sex, mild-to-moderate dental crowding in the upper arch. After randomization and allocation concealment, intervention groups were administered ibuprofen 400 mg, acetaminophen 500 mg, or chewed sugar-free chewing gum immediately after initial archwire placement and every six h, for one week, if the pain persisted. The control group did not receive any pain relief. The outcome was the assessment of pain experience on 100 mm visual analog scales (VAS) at time intervals of T1-2, T2-24 h, and T3- 2 days, T4- 3 days, T5- days 7, and T6- 21 days, at rest, and during bite hard. Statistical analyses were performed using Kruskal-Wallis repeated measures and Mann-Whitney U post-hoc signed-rank tests (α=0.05). Results: chewing gum group experienced more pain relief than ibuprofen at T3- rest and during bite (P ≤ 0.05) and at T4 - rest (P < 0.001). Chewing gum group, during bite, reported more pain relief than acetaminophen (P= 0.03) and control (P= ≤ .001) at T3, and than acetaminophen (P= 0.02) and control (P= ≤ .001) at T3. Conclusions: Chewing gum can be a non-pharmacologic alternative for orthodontic pain relief at 2 and 3 days after initial archwire placement.
Keywords: pain, ibuprofen, acetaminophen, randomized clinical trial
Korean J Orthod
Published online February 3, 2021
Copyright © The Korean Association of Orthodontists.
Diego Junior da Silva Santosa,c,d; Jonas Capelli Jr.b,d
a. PhD Student, Department of Preventive and Community Dentistry, School of Dentistry, Rio de Janeiro State University, Rio de Janeiro, Brazil
b. Full Professor of Orthodontics, Department of Preventive and Community Dentistry, School of Dentistry, Rio de Janeiro State University, Rio de Janeiro, Brazil
c. Private practice
d. Brazilian Board of Orthodontics Certificated
Correspondence to:Diego Junior da Silva Santos
Address: Avenida Ataulfo de Paiva, 1460, apt 601, Leblon, Rio de Janeiro-RJ, Brazil
CEP: 22440-035
Phone: +55 (21) 98027-2082; e-mail: diegorsdrj@gmail.com.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Objectives: To compare the effectiveness of ibuprofen, acetaminophen, and chewing gum for orthodontic pain relief and to assess if chewing gum can be a nonpharmacologic alternative for orthodontics pain relief. Methods: 106 patients were enrolled. The eligibility criteria were age ≥12 years, body mass >50 kg, either sex, mild-to-moderate dental crowding in the upper arch. After randomization and allocation concealment, intervention groups were administered ibuprofen 400 mg, acetaminophen 500 mg, or chewed sugar-free chewing gum immediately after initial archwire placement and every six h, for one week, if the pain persisted. The control group did not receive any pain relief. The outcome was the assessment of pain experience on 100 mm visual analog scales (VAS) at time intervals of T1-2, T2-24 h, and T3- 2 days, T4- 3 days, T5- days 7, and T6- 21 days, at rest, and during bite hard. Statistical analyses were performed using Kruskal-Wallis repeated measures and Mann-Whitney U post-hoc signed-rank tests (α=0.05). Results: chewing gum group experienced more pain relief than ibuprofen at T3- rest and during bite (P ≤ 0.05) and at T4 - rest (P < 0.001). Chewing gum group, during bite, reported more pain relief than acetaminophen (P= 0.03) and control (P= ≤ .001) at T3, and than acetaminophen (P= 0.02) and control (P= ≤ .001) at T3. Conclusions: Chewing gum can be a non-pharmacologic alternative for orthodontic pain relief at 2 and 3 days after initial archwire placement.
Keywords: pain, ibuprofen, acetaminophen, randomized clinical trial