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KJO Korean Journal of Orthodontics

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pISSN 2234-7518
eISSN 2005-372X
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Korean J Orthod

Published online July 20, 2021

Copyright © The Korean Association of Orthodontists.

Micro-computed tomography evaluation of fluoride agents on white spot lesions: an in-vitro study

Sook-Chan Honga, Dong-Yul Leeb, Yae-Jin Kimc

a Postgraduate student, Major in Dentistry, Department of Medicine, Graduate School of Korea University, Seoul, Korea.
b Former professor, Department of Dentistry, College of Medicine, Korea University, Seoul, Korea.
c Clinical Assistant Professor, Department of Orthodontics, Korea University Guro Hospital, Seoul, Korea.

Correspondence to:Yae-Jin Kim.
Clinical Assistant Professor, Department of Orthodontics, Korea University Guro Hospital, 148 Gurodong-ro, Guro-gu, Seoul 08308, Korea
Tel +82-2-2626-1524 e-mail estelle7@korea.ac.kr

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objectives: To investigate remineralizing effect of three fluoride regimens on demineralized enamel around bracket by analyzing mineral density (MD) acquired from micro-computed tomography (micro-CT).
Materials and Method: Forty-eight bracket bonded bovine incisors were prepared to create demineralized enamel (DE) surface. The samples were divided into four groups according to fluoride regimen: 1) no fluoridation, 2) 1.23% acidulated phosphate fluoride (APF) gel, 3) fluoridated toothpaste and 4) 0.05% sodium fluoride mouthwash. Micro-CT was scanned following demineralization (T0), 2 weeks (T1), and 4 weeks (T2) of fluoridation.
Results: APF gel showed highest remineralization of DE at T1-T0 interval among the groups (p < 0.05); followed by toothpaste, mouthwash and no fluoridation. The experimental groups demonstrated significant increase in MD after 4 weeks of application (p < 0.05).
Conclusion: Remineralization effects of three fluoride regimens were manifested through micro-CT analysis, of which the APF gel was most effective.

Keywords: Cariology, Fluoride, Micro-CT

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Korean J Orthod

Published online July 20, 2021

Copyright © The Korean Association of Orthodontists.

Micro-computed tomography evaluation of fluoride agents on white spot lesions: an in-vitro study

Sook-Chan Honga, Dong-Yul Leeb, Yae-Jin Kimc

a Postgraduate student, Major in Dentistry, Department of Medicine, Graduate School of Korea University, Seoul, Korea.
b Former professor, Department of Dentistry, College of Medicine, Korea University, Seoul, Korea.
c Clinical Assistant Professor, Department of Orthodontics, Korea University Guro Hospital, Seoul, Korea.

Correspondence to:Yae-Jin Kim.
Clinical Assistant Professor, Department of Orthodontics, Korea University Guro Hospital, 148 Gurodong-ro, Guro-gu, Seoul 08308, Korea
Tel +82-2-2626-1524 e-mail estelle7@korea.ac.kr

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objectives: To investigate remineralizing effect of three fluoride regimens on demineralized enamel around bracket by analyzing mineral density (MD) acquired from micro-computed tomography (micro-CT).
Materials and Method: Forty-eight bracket bonded bovine incisors were prepared to create demineralized enamel (DE) surface. The samples were divided into four groups according to fluoride regimen: 1) no fluoridation, 2) 1.23% acidulated phosphate fluoride (APF) gel, 3) fluoridated toothpaste and 4) 0.05% sodium fluoride mouthwash. Micro-CT was scanned following demineralization (T0), 2 weeks (T1), and 4 weeks (T2) of fluoridation.
Results: APF gel showed highest remineralization of DE at T1-T0 interval among the groups (p < 0.05); followed by toothpaste, mouthwash and no fluoridation. The experimental groups demonstrated significant increase in MD after 4 weeks of application (p < 0.05).
Conclusion: Remineralization effects of three fluoride regimens were manifested through micro-CT analysis, of which the APF gel was most effective.

Keywords: Cariology, Fluoride, Micro-CT